Vitamin D and Epigenetics?

Fascinating. In “Vitamin D Metabolism, Mechanism of Action, and Clinical Applications,”  Daniel D. Bikle writes:

Vitamin D3 is made in the skin from 7-dehydrocholesterol under the influence of UV light. Vitamin D2 (ergocalciferol) is derived from the plant sterol ergosterol.
…
With the finding of the vitamin D receptor (VDR) in nearly every tissue and the more recent discovery of thousands of VDR binding sites throughout the genome controlling hundreds of genes, the interest in vitamin D and its impact on multiple biologic processes has accelerated tremendously as evidenced by the thousands of publications each year for the past several years.

Looks like Vitamin D affects our epigenome!