I have read that humans hunted the cave bear to extinction. Humans prized their fat highly, so groups would risk injury and death to score a kill. The energy content of the bear was worth it: cave bears gave more energy than the leaner deer, etc.
The oldest positively dated musical instrument was discovered in a cave in Slovenia. It was a flute made by the Neanderthals out of the bone of a cave bear. It has been dated to 50,000 years ago.
Check it out!