“Sleep Habits and Susceptibility to the Common Cold”

In “Sleep Habits and Susceptibility to the Common Cold” (Journal of the American Medical Association, 12 January 2009), Sheldon Cohen, PhD; William J. Doyle, PhD; Cuneyt M. Alper, MD; et al, write:

Methods A total of 153 healthy men and women (age range, 21-55 years) volunteered to participate in the study. For 14 consecutive days, they reported their sleep duration and sleep efficiency (percentage of time in bed actually asleep) for the previous night and whether they felt rested. Average scores for each sleep variable were calculated over the 14-day baseline. Subsequently, participants were quarantined, administered nasal drops containing a rhinovirus, and monitored for the development of a clinical cold (infection in the presence of objective signs of illness) on the day before and for 5 days after exposure.

Results There was a graded association with average sleep duration: participants with less than 7 hours of sleep were 2.94 times (95% confidence interval [CI], 1.18-7.30) more likely to develop a cold than those with 8 hours or more of sleep. The association with sleep efficiency was also graded: participants with less than 92% efficiency were 5.50 times (95% CI, 2.08-14.48) more likely to develop a cold than those with 98% or more efficiency. These relationships could not be explained by differences in prechallenge virus-specific antibody titers, demographics, season of the year, body mass, socioeconomic status, psychological variables, or health practices. The percentage of days feeling rested was not associated with colds.

Arch Intern Med. 2009;169(1):62-67. doi:10.1001/archinternmed.2008.505
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/414701